AMELX - Amelogenin, X isoform - human protein (Function)
 
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AMELX »  Amelogenin, X isoform
 
Gene name:  AMELX
Family name: Amelogenin
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 44 3
GENE REF ISO

Function

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Overview 
Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.  
  • CuratedUniProtKB
GO molecular function 
Growth factor activitydefinition[GO:0008083]  
1
  • ISSBHF-UCL
Hydroxyapatite bindingdefinition[GO:0046848]  
1
  • ISSBHF-UCL
Identical protein bindingdefinition[GO:0042802]  
1
  • ISSBHF-UCL
Protein bindingdefinition[GO:0005515]  
1
  • IPIBHF-UCL
Structural constituent of tooth enameldefinition[GO:0030345]  
3
  • IMPBHF-UCL
GO biological process 
Biomineral tissue developmentdefinition[GO:0031214]  
1
  • TASBHF-UCL
Cell adhesiondefinition[GO:0007155]  
1
  • ISSBHF-UCL
Cell proliferationdefinition[GO:0008283]  
1
  • ISSBHF-UCL
Chondrocyte differentiationdefinition[GO:0002062]  
1
  • ISSBHF-UCL
Enamel mineralizationdefinition[GO:0070166]  
1
  • IMPBHF-UCL
Epithelial to mesenchymal transitiondefinition[GO:0001837]  
1
  • ISSBHF-UCL
Ion homeostasisdefinition[GO:0050801]  
1
  • TASBHF-UCL
Odontogenesis of dentin-containing toothdefinition[GO:0042475]  
1
  • ISSBHF-UCL
Osteoblast differentiationdefinition[GO:0001649]  
1
  • ISSBHF-UCL
Positive regulation of collagen biosynthetic processdefinition[GO:0032967]  
1
  • ISSBHF-UCL
Positive regulation of tooth mineralizationdefinition[GO:0070172]  
1
  • TASBHF-UCL
Signal transductiondefinition[GO:0007165]  
1
  • TASBHF-UCL
Tooth mineralizationdefinition[GO:0034505]  
2
  • IMPBHF-UCL
 

Keywords

Biological process 
Biomineralization  definition   [KW-0091]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: AMELX
GenomeRNAi: 265
PRO: PR:Q99217