ATP6V0B - V-type proton ATPase 21 kDa proteolipid subunit - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
ATP6V0B »  V-type proton ATPase 21 kDa proteolipid subunit  (V-ATPase 21 kDa proteolipid subunit)
 
Protein also known as:  Vacuolar proton pump 21 kDa proteolipid subunit.
Gene name:  ATP6V0B
Entry whose protein(s) existence is based on evidence at transcript level
extend overview
1 13 2
GENE REF ISO

Function

 show evidences
Overview 
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.  
  • CuratedUniProtKB
GO molecular function 
Hydrogen ion transmembrane transporter activitydefinition[GO:0015078] silver  
  • IEAInterPro 2 GO
Transporter activitydefinition[GO:0005215]  
1
  • TASPINC
GO biological process 
ATP hydrolysis coupled proton transportdefinition[GO:0015991] silver  
  • IEAInterPro 2 GO
Proton transportdefinition[GO:0015992]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Epithelial cell signaling in Helicobacter pylori infection  hsa05120+533  
Lysosome  hsa04142+533  
Metabolic pathways  hsa01100+533  
Oxidative phosphorylation  hsa00190+533  
Phagosome  hsa04145+533  
Rheumatoid arthritis  hsa05323+533  
Synaptic vesicle cycle  hsa04721+533  
Tuberculosis  hsa05152+533  
Vibrio cholerae infection  hsa05110+533  
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Signal Transduction  REACT_111102  
Transmembrane transport of small molecules  REACT_15518  
 
More information is available from:
 

Keywords

Biological process 
Hydrogen ion transport  definition   [KW-0375]
Ion transport  definition   [KW-0406]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ATP6V0B
GenomeRNAi: 533
PRO: PR:Q99437