PCYT2 - Ethanolamine-phosphate cytidylyltransferase - human protein (Function)
 
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Protein
Gene
References

 
PCYT2 »  Ethanolamine-phosphate cytidylyltransferase   [ EC 2.7.7.14 ]
 
Protein also known as:  CTP:phosphoethanolamine cytidylyltransferase.
Gene name:  PCYT2
Family name: Cytidylyltransferase
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine.  
  • CuratedUniProtKB
GO molecular function 
Ethanolamine-phosphate cytidylyltransferase activitydefinition[GO:0004306]  
1
  • TASUniProtKB
GO biological process 
Phosphatidylethanolamine biosynthetic processdefinition[GO:0006646]  
  • IEAUniPathway
Phospholipid biosynthetic processdefinition[GO:0008654]  
1
  • TASUniProtKB
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.7.14: CTP + ethanolamine phosphate diphosphate + CDP-ethanolamine.  
  • CuratedUniProtKB
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Glycerophospholipid metabolism  hsa00564+5833  
Metabolic pathways  hsa01100+5833  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 

Keywords

Biological process 
Lipid biosynthesis  definition   [KW-0444]
Lipid metabolism  definition   [KW-0443]
Phospholipid biosynthesis  definition   [KW-0594]
Phospholipid metabolism  definition   [KW-1208]
Molecular function 
Nucleotidyltransferase  definition   [KW-0548]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 5833
PRO: PR:Q99447