CDCA3 - Cell division cycle-associated protein 3 - human protein (Function)
 
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CDCA3 »  Cell division cycle-associated protein 3
 
Protein also known as:  Trigger of mitotic entry protein 1 (TOME-1).
Gene name:  CDCA3
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity).  
  • CuratedUniProtKB
GO biological process 
Mitosisdefinition[GO:0007067]  
  • IEAUniProtKB KW
Protein ubiquitinationdefinition[GO:0016567]  
  • IEAUniPathway
Pathways 
This protein is involved in the following pathway
 

Keywords

Biological process 
Cell cycle  definition   [KW-0131]
Cell division  definition   [KW-0132]
Mitosis  definition   [KW-0498]
Ubl conjugation pathway  definition   [KW-0833]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CDCA3
GenomeRNAi: 83461
PRO: PR:Q99618