EPYC - Epiphycan - human protein (Sequence)
 
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Protein
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References

 
EPYC »  Epiphycan
 
Protein also known as:  Small chondroitin/dermatan sulfate proteoglycan.
Gene name:  EPYC
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Displayed isoform: Iso 1

 
 
Isoform Iso 1   322 aaMass: 36637 Da,  pI: 4.67
MKTLAGLVLG LVIFDAAVTA PTLESINYDS ETYDATLEDL DNLYNYENIP VDKVEIEIAT VMPSGNRELL TPPPQPEKAQ EEEEEEESTP RLIDGSSPQE PEFTGVLGPH TNEDFPTCLL CTCISTTVYC DDHELDAIPP LPKNTAYFYS RFNRIKKINK NDFASLSDLK RIDLTSNLIS EIDEDAFRKL PQLRELVLRD NKIRQLPELP TTLTFIDISN NRLGRKGIKQ EAFKDMYDLH HLYLTDNNLD HIPLPLPENL RALHLQNNNI LEMHEDTFCN VKNLTYIRKA LEDIRLDGNP INLSKTPQAY MCLPRLPVGS LV

Sequence

 show evidences
PTM 
The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64 (By similarity).  
  • CuratedUniProtKB
 

Keywords

Coding sequence diversity 
Polymorphism  definition   [KW-0621]
Domain 
Leucine-rich repeat  definition   [KW-0433]
Repeat  definition   [KW-0677]
Signal  definition   [KW-0732]
PTM 
Disulfide bond  definition   [KW-1015]
Glycoprotein  definition   [KW-0325]
Proteoglycan  definition   [KW-0654]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Family and domain databases
InterPro: IPR000372 [ LRR-contain N ]
InterPro: IPR001611 [ Leu-rich rpt ]
InterPro: IPR027217 [ Epiphycan ]
PANTHER: PTHR24371:SF4 [ PTHR24371:SF4 ]
Pfam: PF01462 [ LRRNT ]
PROSITE: PS51450 [ LRR ]
SMART: SM00013 [ LRRNT ]
Genome annotation databases
Ensembl: Transcript: ENST00000261172;  Protein: ENSP00000261172;  Gene: ENSG00000083782.
Ensembl: Transcript: ENST00000551767;  Protein: ENSP00000448272;  Gene: ENSG00000083782.
KEGG: hsa:1833
UCSC: uc001tbk.3
Organism-specific databases
MGI: MGI:107942 [ Epyc ]
PTM databases
PhosphoSite: Q99645
Phylogenomic databases
eggNOG: NOG314832
HOGENOM: HOG000273909
HOVERGEN: HBG006850
InParanoid: Q99645
KO: K08127
OMA: CDDHELD
OrthoDB: EOG757CXS
PhylomeDB: Q99645
Sequence databases
CCDS: CCDS31870.1 [ Q99645-1 ]
EMBL: mRNA:  AK290642 . Translation:  BAF83331.1 .
EMBL: mRNA:  U59111 . Translation:  AAC50945.1 .
EMBL: Genomic DNA:  CH471054 . Translation:  EAW97444.1 .
EMBL: mRNA:  BC030958 . Translation:  AAH30958.1 .
IPI: IPI00007444
RefSeq: Protein:  NP_004941.2. Nucleotide sequence:  NM_004950.4.
UniProtKB: Q99645
Protocols and materials databases
DNASU: 1833