FEZ1 - Fasciculation and elongation protein zeta-1 - human protein (Function)
 
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Protein
Gene
References

 
FEZ1 »  Fasciculation and elongation protein zeta-1
 
Protein also known as:  Zygin-1.
Gene name:  FEZ1
Family name: Zygin
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 38 2
GENE REF ISO

Function

 show evidences
Overview 
May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.  
3
  • UniProtKB
GO molecular function 
Gamma-tubulin bindingdefinition[GO:0043015] silver  
1
  • Ortholog Compara
Protein bindingdefinition[GO:0005515]  
4
  • IntAct
Protein kinase C bindingdefinition[GO:0005080] silver  
1
  • Ortholog Compara
Protein N-terminus bindingdefinition[GO:0047485] silver  
1
  • Ortholog Compara
GO biological process 
Axon guidancedefinition[GO:0007411]  
1
  • PINC
Cell adhesiondefinition[GO:0007155]  
1
  • PINC
Cellular response to growth factor stimulusdefinition[GO:0071363] silver  
1
  • Ortholog Compara
Establishment of mitochondrion localizationdefinition[GO:0051654] silver  
1
  • Ortholog Compara
Nervous system developmentdefinition[GO:0007399]  
1
  • PINC
Positive regulation of neuron projection developmentdefinition[GO:0010976] silver  
1
  • Ortholog Compara
Transportdefinition[GO:0006810]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: FEZ1
GenomeRNAi: 9638
PRO: PR:Q99689