ABCA3 - ATP-binding cassette sub-family A member 3 - human protein (Function)
 
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Protein
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References

 
ABCA3 »  ATP-binding cassette sub-family A member 3
 
Protein also known as:  ATP-binding cassette transporter 3 (ATP-binding cassette 3).
Gene name:  ABCA3
Family name: ABC transporter » ABCA
Entry whose protein(s) existence is based on evidence at protein level
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1 72 1
GENE REF ISO

Function

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Overview 
Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the atp-binding cassette (abc) superfamily  3.A.1.211.5  
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
ATPase activity, coupled to transmembrane movement of substancesdefinition[GO:0042626]  
1
  • TASPINC
Transporter activitydefinition[GO:0005215]  
1
  • TASPINC
GO biological process 
ATP catabolic processdefinition[GO:0006200]  
1
  • TASGOC
Metabolic processdefinition[GO:0008152]  
1
  • TASGOC
Response to drugdefinition[GO:0042493]  
1
  • TASPINC
Transportdefinition[GO:0006810]  
1
  • IDAMGI
Pathways 
According to KEGG, this protein belongs to the following pathway:
ABC transporters  hsa02010+21  
According to Reactome, this protein belongs to the following pathway:
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ABCA3
GenomeRNAi: 21
PRO: PR:Q99758