OCSTAMP - Osteoclast stimulatory transmembrane protein - human protein (Function)
 
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OCSTAMP »  Osteoclast stimulatory transmembrane protein  (OC-STAMP)
 
Gene name:  OCSTAMP
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Probable cell surface receptor that plays a role in cellular fusion and cell differentiation. Cooperates with DCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Involved in osteoclast bone resorption. Promotes osteoclast differentiation and may play a role in the multinucleated osteoclast maturation (By similarity).  
  • CuratedUniProtKB
GO biological process 
Cellular response to estrogen stimulusdefinition[GO:0071391]  
  • ISSOrtholog Curator
Cellular response to tumor necrosis factordefinition[GO:0071356]  
  • ISSOrtholog Curator
Multinuclear osteoclast differentiationdefinition[GO:0072674]  
  • ISSOrtholog Curator
Positive regulation of macrophage fusiondefinition[GO:0034241] silver  
  • IEAOrtholog Compara
Positive regulation of osteoclast differentiationdefinition[GO:0045672]  
  • ISSOrtholog Curator
Positive regulation of osteoclast proliferationdefinition[GO:0090290]  
  • ISSOrtholog Curator
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Technical term 
Reference proteome  definition   [KW-1185]
 

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