CORO1B - Coronin-1B - human protein (Function)
 
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Protein
Gene
References

 
CORO1B »  Coronin-1B
 
Gene name:  CORO1B
Family name: WD repeat coronin
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity).  
1
  • CuratedUniProtKB
GO molecular function 
Actin filament bindingdefinition[GO:0051015]  
1
  • IDAUniProtKB
  • IBARefGenome
Arp2/3 complex bindingdefinition[GO:0071933]  
2
  • IDAUniProtKB
Identical protein bindingdefinition[GO:0042802]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
  • IPIUniProtKB
GO biological process 
Actin cytoskeleton organizationdefinition[GO:0030036] silver  
  • IBARefGenome
Actin filament branchingdefinition[GO:0090135]  
1
  • IDAUniProtKB
Actin filament bundle assemblydefinition[GO:0051017]  
1
  • IDAUniProtKB
Cell migrationdefinition[GO:0016477]  
1
  • IDAUniProtKB
Endothelial cell chemotaxisdefinition[GO:0035767]  
1
  • IDAUniProtKB
Negative regulation of Arp2/3 complex-mediated actin nucleationdefinition[GO:0034316]  
2
  • IDAUniProtKB
Positive regulation of lamellipodium morphogenesisdefinition[GO:2000394]  
1
  • IDAUniProtKB
Protein localization to cell leading edgedefinition[GO:1902463]  
1
  • IDAUniProtKB
Ruffle organizationdefinition[GO:0031529]  
1
  • IDAUniProtKB
Wound healingdefinition[GO:0042060]  
1
  • IDAUniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 57175
PRO: PR:Q9BR76