ADPGK - ADP-dependent glucokinase - human protein (Function)
 
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ADPGK »  ADP-dependent glucokinase   [ EC 2.7.1.147 ]  (ADPGK)
 
Protein also known as:  RbBP-35.
Gene name:  ADPGK
Entry whose protein(s) existence is based on evidence at protein level
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1 22 6
GENE REF ISO

Function

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Overview 
Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity).  
  • CuratedUniProtKB
GO molecular function 
ADP-specific glucokinase activitydefinition[GO:0043843]  
  • IEAEC 2 GO
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
GO biological process 
Glycolytic processdefinition[GO:0006096]  
  • IEAUniPathway
Phosphorylationdefinition[GO:0016310]  
  • IEAUniProtKB KW
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.1.147: ADP + D-glucose AMP + D-glucose 6-phosphate.  
  • CuratedUniProtKB
It requires the following cofactor
Binds 1 magnesium ion per subunit (By similarity).  
  • CuratedUniProtKB
Pathways 
This protein is involved in the following pathway
  • CuratedUniProtKB
According to KEGG, this protein belongs to the following pathways:
Glycolysis / Gluconeogenesis  hsa00010+83440  
Metabolic pathways  hsa01100+83440  
 

Keywords

Biological process 
Glycolysis  definition   [KW-0324]
Molecular function 
Kinase  definition   [KW-0418]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ADP-specific_glucokinase
GenomeRNAi: 83440
PRO: PR:Q9BRR6