AGMAT - Agmatinase, mitochondrial - human protein (Function)
 
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AGMAT »  Agmatinase, mitochondrial   [ EC 3.5.3.11 ]
 
Protein also known as:  Agmatine ureohydrolase (AUH).
Gene name:  AGMAT
Family name: Arginase » Agmatinase
Entry whose protein(s) existence is based on evidence at protein level
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1 18 1
GENE REF ISO

Function

 show evidences
GO molecular function 
Agmatinase activitydefinition[GO:0008783]  
  • IEAEC 2 GO
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
GO biological process 
Putrescine biosynthetic process from argininedefinition[GO:0033388]  
  • IEAUniPathway
Spermidine biosynthetic processdefinition[GO:0008295]  
  • IEAUniProtKB KW
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.5.3.11: Agmatine + H(2)O putrescine + urea.  
1
  • CuratedUniProtKB
It requires the following cofactor
Manganese (Potential).  
  • CuratedUniProtKB
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Arginine and proline metabolism  hsa00330+79814  
Metabolic pathways  hsa01100+79814  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 

Keywords

Biological process 
Putrescine biosynthesis  definition   [KW-0661]
Spermidine biosynthesis  definition   [KW-0745]
Molecular function 
Hydrolase  definition   [KW-0378]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Agmatinase
GenomeRNAi: 79814
PRO: PR:Q9BSE5