APOO - Apolipoprotein O - human protein (Function)
 
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APOO »  Apolipoprotein O
 
Protein also known as:  Protein FAM121B.
Gene name:  APOO
Family name: Apolipoprotein O
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.  
1
  • CuratedUniProtKB
GO biological process 
Lipid transportdefinition[GO:0006869]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Lipid transport  definition   [KW-0445]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Apolipoprotein_O
GenomeRNAi: 79135
PRO: PR:Q9BUR5