TMEM109 - Transmembrane protein 109 - human protein (Function)
 
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Protein
Gene
References

 
TMEM109 »  Transmembrane protein 109
 
Protein also known as:  Mitsugumin-23 (Mg23).
Gene name:  TMEM109
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death (PubMed23542032). Can form voltage-gated calcium and potassium channels in vitro (By similarity).  
3
  • UniProtKB
According to TCDB this is a transporter from family:
the mitsugumin 23 (mg23) family  1.A.74.1.2  
GO molecular function 
Voltage-gated ion channel activitydefinition[GO:0005244]  
1
  • UniProtKB KW
GO biological process 
Cellular response to gamma radiationdefinition[GO:0071480]  
1
  • MGI
Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatordefinition[GO:0042771] silver  
1
  • Ortholog Compara
Ion transportdefinition[GO:0006811]  
1
  • UniProtKB KW
Negative regulation of cell deathdefinition[GO:0060548]  
1
  • MGI
Regulation of ion transmembrane transportdefinition[GO:0034765]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 79073
PRO: PR:Q9BVC6