ACAT2 - Acetyl-CoA acetyltransferase, cytosolic - human protein (Function)
 
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Protein
Gene
References

 
ACAT2 »  Acetyl-CoA acetyltransferase, cytosolic   [ EC 2.3.1.9 ]
 
Protein also known as:  Acetyl-CoA transferase-like protein.
Gene name:  ACAT2
Family name: Thiolase
Entry whose protein(s) existence is based on evidence at protein level
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1 29 1
GENE REF ISO

Function

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GO molecular function 
Acetyl-CoA C-acetyltransferase activitydefinition[GO:0003985]  
1
  • IDABHF-UCL
GO biological process 
Lipid metabolic processdefinition[GO:0006629]  
1
  • ICBHF-UCL
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.3.1.9: 2 acetyl-CoA CoA + acetoacetyl-CoA.  
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Butanoate metabolism  hsa00650+39  
Fat digestion and absorption  hsa04975+39  
Fatty acid metabolism  hsa00071+39  
Glyoxylate and dicarboxylate metabolism  hsa00630+39  
Lysine degradation  hsa00310+39  
Metabolic pathways  hsa01100+39  
Propanoate metabolism  hsa00640+39  
Pyruvate metabolism  hsa00620+39  
Synthesis and degradation of ketone bodies  hsa00072+39  
Terpenoid backbone biosynthesis  hsa00900+39  
Tryptophan metabolism  hsa00380+39  
Valine, leucine and isoleucine degradation  hsa00280+39  
 
More information is available from:
 

Keywords

Molecular function 
Acyltransferase  definition   [KW-0012]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ACAT2
GenomeRNAi: 39
PRO: PR:Q9BWD1