ADGRE3 - Adhesion G protein-coupled receptor E3 - human protein (Function)
 
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ADGRE3 »  Adhesion G protein-coupled receptor E3
 
Protein also known as:  EGF-like module-containing mucin-like hormone receptor-like 3.
Gene name:  ADGRE3
Entry whose protein(s) existence is based on evidence at protein level
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1 31 3
GENE REF ISO

Function

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Overview 
Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes-derived macrophages and activated neutrophils.  
2
  • UniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
1
  • InterPro 2 GO
G-protein coupled receptor activitydefinition[GO:0004930]  
1
  • UniProtKB KW
GO biological process 
Cell surface receptor signaling pathwaydefinition[GO:0007166] silver  
1
  • InterPro 2 GO
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • UniProtKB KW
Enzymatic activity 
 
More information is available from:
Pathways 
According to Reactome, this protein belongs to the following pathway:
Class B/2 (Secretin family receptors)  R-HSA-373080  
Note 
Has no murine ortholog.  
1
  • UniProtKB
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: EMR3
GenomeRNAi: 84658
PRO: PR:Q9BY15