SLC19A3 - Thiamine transporter 2 - human protein (Function)
 
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Protein
Gene
References

 
SLC19A3 »  Thiamine transporter 2  (ThTr2)
 
Protein also known as:  Solute carrier family 19 member 3.
Gene name:  SLC19A3
Entry whose protein(s) existence is based on evidence at protein level
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1 34 1
GENE REF ISO

Function

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Overview 
Mediates high affinity thiamine uptake, propably via a proton anti-port mechanism. Has no folate transport activity.  
1
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the reduced folate carrier (rfc) family  2.A.48.2.3  
GO molecular function 
Thiamine uptake transmembrane transporter activitydefinition[GO:0015403]  
  • ISSOrtholog Curator
GO biological process 
Drug transmembrane transportdefinition[GO:0006855]  
  • ISSOrtholog Curator
Thiamine transmembrane transportdefinition[GO:0071934]  
  • ISSOrtholog Curator
Transmembrane transportdefinition[GO:0055085]  
  • ISSOrtholog Curator
Vitamin transmembrane transportdefinition[GO:0035461]  
  • ISSOrtholog Curator
Pathways 
According to KEGG, this protein belongs to the following pathway:
Vitamin digestion and absorption  hsa04977+80704  
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Metabolism  REACT_111217  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: SLC19A3
GenomeRNAi: 80704
PRO: PR:Q9BZV2
Chemistry
GuidetoPHARMACOLOGY: 1016