SLC19A3 - Thiamine transporter 2 - human protein (Function)
 
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Protein
Gene
References

 
SLC19A3 »  Thiamine transporter 2  (ThTr2)
 
Protein also known as:  Solute carrier family 19 member 3.
Gene name:  SLC19A3
Entry whose protein(s) existence is based on evidence at protein level
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1 48 1
GENE REF ISO

Function

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Overview 
Mediates high affinity thiamine uptake, propably via a proton anti-port mechanism. Has no folate transport activity.  
2
  • UniProtKB
According to TCDB this is a transporter from family:
the reduced folate carrier (rfc) family  2.A.48.2.3  
GO molecular function 
Thiamine uptake transmembrane transporter activitydefinition[GO:0015403]  
2
  • Ortholog Curator
  • RefGenome
GO biological process 
Drug transmembrane transportdefinition[GO:0006855]  
1
  • RefGenome
Thiamine transmembrane transportdefinition[GO:0071934]  
1
  • RefGenome
Pathways 
According to KEGG, this protein belongs to the following pathway:
Vitamin digestion and absorption  hsa04977+80704  
According to Reactome, this protein belongs to the following pathway:
Vitamin B1 (thiamin) metabolism  R-HSA-196819  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: SLC19A3
GenomeRNAi: 80704
PRO: PR:Q9BZV2
Chemistry
GuidetoPHARMACOLOGY: 1016