PHACTR1 - Phosphatase and actin regulator 1 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
PHACTR1 »  Phosphatase and actin regulator 1
 
Gene name:  PHACTR1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 21 2
GENE REF ISO

Function

 show evidences
Overview 
Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Plays a role in cell motility. Plays a role in the formation of tubules by endothelial cells. Regulates PPP1CA activity. Required for normal cell survival.  
2
  • CuratedUniProtKB
GO molecular function 
Actin bindingdefinition[GO:0003779]  
  • ISSOrtholog Curator
Protein phosphatase inhibitor activitydefinition[GO:0004864]  
  • IEAUniProtKB KW
GO biological process 
Actin cytoskeleton reorganizationdefinition[GO:0031532]  
  • ISSOrtholog Curator
Actomyosin structure organizationdefinition[GO:0031032]  
1
  • IMPUniProtKB
Cell motilitydefinition[GO:0048870]  
1
  • IMPUniProtKB
Stress fiber assemblydefinition[GO:0043149]  
1
  • IMPUniProtKB
 

Keywords

Molecular function 
Protein phosphatase inhibitor  definition   [KW-0650]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 221692
PRO: PR:Q9C0D0