WNT10A - Protein Wnt-10a - human protein (Function)
 
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WNT10A »  Protein Wnt-10a
 
Gene name:  WNT10A
Family name: Wnt
Entry whose protein(s) existence is based on evidence at protein level
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1 36 1
GENE REF ISO

Function

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Overview 
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters.  
  • CuratedUniProtKB
GO molecular function 
Frizzled bindingdefinition[GO:0005109] silver  
  • IBARefGenome
GO biological process 
Cell fate commitmentdefinition[GO:0045165] silver  
  • IBARefGenome
Cellular response to transforming growth factor beta stimulusdefinition[GO:0071560]  
1
  • IEPUniProtKB
Epidermis morphogenesisdefinition[GO:0048730]  
1
  • IMPBHF-UCL
Hair follicle developmentdefinition[GO:0001942]  
2
  • IMPBHF-UCL
Hair follicle morphogenesisdefinition[GO:0031069]  
1
  • IMPBHF-UCL
Neural crest cell differentiationdefinition[GO:0014033] silver  
  • IEAOrtholog Compara
Neuron differentiationdefinition[GO:0030182] silver  
  • IBARefGenome
Odontogenesisdefinition[GO:0042476]  
2
  • IMPBHF-UCL
Positive regulation of gene expressiondefinition[GO:0010628] silver  
  • IEAOrtholog Compara
Regulation of odontogenesis of dentin-containing toothdefinition[GO:0042487] silver  
  • IEAOrtholog Compara
Sebaceous gland developmentdefinition[GO:0048733]  
1
  • IMPBHF-UCL
Skin developmentdefinition[GO:0043588]  
2
  • IMPBHF-UCL
Tongue developmentdefinition[GO:0043586]  
2
  • IMPBHF-UCL
Wnt signaling pathwaydefinition[GO:0016055] silver  
  • IBARefGenome
Pathways 
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Biological process 
Wnt signaling pathway  definition   [KW-0879]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: WNT10A
GenomeRNAi: 80326
PRO: PR:Q9GZT5