MRPL18 - 39S ribosomal protein L18, mitochondrial - human protein (Function)
 
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MRPL18 »  39S ribosomal protein L18, mitochondrial
 
Gene name:  MRPL18
Family name: Ribosomal protein L18P
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA.  
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  • CuratedUniProtKB
GO molecular function 
5S rRNA bindingdefinition[GO:0008097]  
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  • IDAUniProtKB
Structural constituent of ribosomedefinition[GO:0003735]  
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  • NASUniProtKB
GO biological process 
rRNA import into mitochondriondefinition[GO:0035928]  
1
  • IDAUniProtKB
Translationdefinition[GO:0006412]  
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  • NASUniProtKB
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Molecular function 
Chaperone  definition   [KW-0143]
Ribonucleoprotein  definition   [KW-0687]
Ribosomal protein  definition   [KW-0689]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MRPL18
GenomeRNAi: 29074
PRO: PR:Q9H0U6