ALX4 - Homeobox protein aristaless-like 4 - human protein (Function)
 
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ALX4 »  Homeobox protein aristaless-like 4
 
Gene name:  ALX4
Family name: Paired homeobox
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development.  
1
  • CuratedUniProtKB
GO molecular function 
DNA bindingdefinition[GO:0003677]  
1
  • NASUniProtKB
HMG box domain bindingdefinition[GO:0071837] silver  
  • IEAOrtholog Compara
Protein heterodimerization activitydefinition[GO:0046982] silver  
  • IEAOrtholog Compara
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAOrtholog Compara
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAOrtholog Compara
GO biological process 
Anterior/posterior pattern specificationdefinition[GO:0009952] silver  
  • IEAOrtholog Compara
Digestive tract developmentdefinition[GO:0048565] silver  
  • IEAOrtholog Compara
Embryonic digit morphogenesisdefinition[GO:0042733] silver  
  • IEAOrtholog Compara
Embryonic forelimb morphogenesisdefinition[GO:0035115] silver  
  • IEAOrtholog Compara
Embryonic hindlimb morphogenesisdefinition[GO:0035116] silver  
  • IEAOrtholog Compara
Embryonic skeletal system morphogenesisdefinition[GO:0048704] silver  
  • IEAOrtholog Compara
Hair follicle developmentdefinition[GO:0001942]  
1
  • IMPUniProtKB
Muscle organ developmentdefinition[GO:0007517] silver  
  • IEAOrtholog Compara
Palate developmentdefinition[GO:0060021] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Post-embryonic developmentdefinition[GO:0009791] silver  
  • IEAOrtholog Compara
Regulation of apoptotic processdefinition[GO:0042981] silver  
  • IEAOrtholog Compara
Skeletal system developmentdefinition[GO:0001501]  
1
  • NASUniProtKB
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ALX4
GenomeRNAi: 60529
PRO: PR:Q9H161