SLK - STE20-like serine/threonine-protein kinase - human protein (Function)
 
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SLK »  STE20-like serine/threonine-protein kinase   [ EC 2.7.11.1 ]  (STE20-like kinase)
 
Protein also known as:  STE20-related serine/threonine-protein kinase (STE20-related kinase).
Gene name:  SLK
Entry whose protein(s) existence is based on evidence at protein level
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1 34 2
GENE REF ISO

Function

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Overview 
Mediates apoptosis and actin stress fiber dissolution (By similarity).  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Identical protein bindingdefinition[GO:0042802]  
1
  • IPIIntAct
Protein homodimerization activitydefinition[GO:0042803]  
1
  • IDAUniProtKB
Protein serine/threonine kinase activitydefinition[GO:0004674]  
1
  • IDAUniProtKB
Receptor signaling protein serine/threonine kinase activitydefinition[GO:0004702] silver  
  • IBARefGenome
GO biological process 
Apoptotic processdefinition[GO:0006915]  
  • IEAUniProtKB KW
Intracellular signal transductiondefinition[GO:0035556] silver  
  • IBARefGenome
Protein autophosphorylationdefinition[GO:0046777]  
1
  • IDAUniProtKB
Signal transductiondefinition[GO:0007165] silver  
  • IBARefGenome
Signal transduction by phosphorylationdefinition[GO:0023014] silver  
  • IBARefGenome
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.1: ATP + a protein ADP + a phosphoprotein.  
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Oocyte meiosis  hsa04114+9748  
 

Keywords

Biological process 
Apoptosis  definition   [KW-0053]
Molecular function 
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: SLK_(gene)
GenomeRNAi: 9748
PRO: PR:Q9H2G2
Chemistry
GuidetoPHARMACOLOGY: 2200