ADNP - Activity-dependent neuroprotector homeobox protein - human protein (Function)
 
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ADNP »  Activity-dependent neuroprotector homeobox protein
 
Protein also known as:  Activity-dependent neuroprotective protein.
Gene name:  ADNP
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.  
1
  • UniProtKB
GO molecular function 
Beta-tubulin bindingdefinition[GO:0048487] silver  
1
  • Ortholog Compara
Chromatin bindingdefinition[GO:0003682] silver  
1
  • Ortholog Compara
Copper ion bindingdefinition[GO:0005507] silver  
1
  • Ortholog Compara
DNA bindingdefinition[GO:0003677]  
1
  • UniProtKB KW
Peptide bindingdefinition[GO:0042277] silver  
1
  • Ortholog Compara
Protein bindingdefinition[GO:0005515]  
2
  • IntAct
GO biological process 
Activation of protein kinase activitydefinition[GO:0032147] silver  
1
  • Ortholog Compara
Cellular response to extracellular stimulusdefinition[GO:0031668] silver  
1
  • Ortholog Compara
Estrous cycledefinition[GO:0044849] silver  
1
  • Ortholog Compara
Negative regulation of gene expressiondefinition[GO:0010629] silver  
1
  • Ortholog Compara
Negative regulation of neuron apoptotic processdefinition[GO:0043524] silver  
1
  • Ortholog Compara
Negative regulation of protein bindingdefinition[GO:0032091] silver  
1
  • Ortholog Compara
Negative regulation of synaptic transmissiondefinition[GO:0050805] silver  
1
  • Ortholog Compara
Nitric oxide homeostasisdefinition[GO:0033484] silver  
1
  • Ortholog Compara
Positive regulation of axon extensiondefinition[GO:0045773] silver  
1
  • Ortholog Compara
Positive regulation of cGMP biosynthetic processdefinition[GO:0030828] silver  
1
  • Ortholog Compara
Positive regulation of peptidyl-tyrosine phosphorylationdefinition[GO:0050731] silver  
1
  • Ortholog Compara
Positive regulation of synapse assemblydefinition[GO:0051965] silver  
1
  • Ortholog Compara
Regulation of protein ADP-ribosylationdefinition[GO:0010835] silver  
1
  • Ortholog Compara
Regulation of transcription, DNA-templateddefinition[GO:0006355]  
1
  • UniProtKB KW
Response to carbohydratedefinition[GO:0009743] silver  
1
  • Ortholog Compara
Response to inorganic substancedefinition[GO:0010035] silver  
1
  • Ortholog Compara
Short-term memorydefinition[GO:0007614] silver  
1
  • Ortholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
1
  • UniProtKB KW
Note 
When isolated from the sequence, neuroprotective peptide (NAP) provides neuroprotection against the beta-amyloid peptide.  
1
  • UniProtKB
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 23394
PRO: PR:Q9H2P0