DPEP3 - Dipeptidase 3 - human protein (Function)
 
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DPEP3 »  Dipeptidase 3   [ EC 3.4.13.19 ]
 
Gene name:  DPEP3
Family name: Peptidase M19
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Probable metalloprotease which hydrolyzes cystinyl-bis-glycine. May be involved in meiosis (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Dipeptidase activitydefinition[GO:0016805]  
  • IEAUniProtKB KW
Dipeptidyl-peptidase activitydefinition[GO:0008239] silver  
  • IEAInterPro 2 GO
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Metalloexopeptidase activitydefinition[GO:0008235] silver  
  • IEAInterPro 2 GO
GO biological process 
Male meiosisdefinition[GO:0007140]  
  • ISSOrtholog Curator
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.4.13.19: Hydrolysis of dipeptides.  
  • CuratedUniProtKB
It requires the following cofactor
Zinc (By similarity).  
  • CuratedUniProtKB
It is regulated in the following manner
Inhibited by L-penicillamine (By similarity).  
  • CuratedUniProtKB
 
More information is available from:
 

Keywords

Biological process 
Meiosis  definition   [KW-0469]
Molecular function 
Dipeptidase  definition   [KW-0224]
Hydrolase  definition   [KW-0378]
Metalloprotease  definition   [KW-0482]
Protease  definition   [KW-0645]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: DPEP3
GenomeRNAi: 64180
PRO: PR:Q9H4B8