ACSS3 - Acyl-CoA synthetase short-chain family member 3, mitochondrial - human protein (Function)
 
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ACSS3 »  Acyl-CoA synthetase short-chain family member 3, mitochondrial   [ EC 6.2.1.1 ]
 
Protein also known as:  Acyl-CoA synthetase short-chain family member 3.
Gene name:  ACSS3
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Acetate-CoA ligase activitydefinition[GO:0003987]  
  • IEAEC 2 GO
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
GO biological process 
Metabolic processdefinition[GO:0008152] silver  
  • IEAInterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 6.2.1.1: ATP + acetate + CoA AMP + diphosphate + acetyl-CoA.  
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathways:
Metabolic pathways  hsa01100+79611  
Propanoate metabolism  hsa00640+79611  
 

Keywords

Molecular function 
Ligase  definition   [KW-0436]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 79611
PRO: PR:Q9H6R3