FKRP - Fukutin-related protein - human protein (Function)
 
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Protein
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References

 
FKRP »  Fukutin-related protein   [ EC 2.-.-.- ]
 
Gene name:  FKRP
Family name: LicD transferase
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Transferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.  
2
  • UniProtKB
GO molecular function 
Transferase activitydefinition[GO:0016740]  
1
  • UniProtKB KW
GO biological process 
Protein O-linked mannosylationdefinition[GO:0035269]  
1
  • UniProtKB
Protein processingdefinition[GO:0016485] silver  
1
  • Ortholog Compara
Pathways 
This protein is involved in the following pathway
Protein modification; protein glycosylation  
2
  • UniProtKB
 

Keywords

Molecular function 
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 79147
PRO: PR:Q9H9S5