CERS4 - Ceramide synthase 4 - human protein (Function)
 
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Protein
Gene
References

 
CERS4 »  Ceramide synthase 4  (CerS4)
 
Protein also known as:  LAG1 longevity assurance homolog 4.
Gene name:  CERS4
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAInterPro 2 GO
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
Sphingosine N-acyltransferase activitydefinition[GO:0050291] silver  
  • IEAOrtholog Compara
GO biological process 
Ceramide biosynthetic processdefinition[GO:0046513] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 

Keywords

Biological process 
Lipid biosynthesis  definition   [KW-0444]
Lipid metabolism  definition   [KW-0443]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 79603
PRO: PR:Q9HA82