ADGRL3 - Adhesion G protein-coupled receptor L3 - human protein (Function)
 
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ADGRL3 »  Adhesion G protein-coupled receptor L3
 
Protein also known as:  Calcium-independent alpha-latrotoxin receptor 3 (CIRL-3).
Gene name:  ADGRL3
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells (PubMed26235030). Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex.  
3
  • UniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509]  
1
  • UniProtKB
Carbohydrate bindingdefinition[GO:0030246]  
1
  • UniProtKB KW
G-protein coupled receptor activitydefinition[GO:0004930]  
1
  • UniProtKB
Protein bindingdefinition[GO:0005515]  
1
  • UniProtKB
GO biological process 
Cell surface receptor signaling pathwaydefinition[GO:0007166] silver  
1
  • InterPro 2 GO
Cell-cell adhesiondefinition[GO:0098609]  
1
  • UniProtKB
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • UniProtKB
Neuron migrationdefinition[GO:0001764]  
1
  • Ortholog Curator
Positive regulation of synapse assemblydefinition[GO:0051965] silver  
1
  • Ortholog Compara
Synapse assemblydefinition[GO:0007416]  
1
  • Ortholog Curator
Enzymatic activity 
 
More information is available from:
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 23284
PRO: PR:Q9HAR2