RRAGC - Ras-related GTP-binding protein C - human protein (Function)
 
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RRAGC »  Ras-related GTP-binding protein C  (RagC)
 
Protein also known as:  GTPase-interacting protein 2.
Gene name:  RRAGC
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.  
1
  • CuratedUniProtKB
GO molecular function 
GDP bindingdefinition[GO:0019003]  
1
  • IDAUniProtKB
GTP bindingdefinition[GO:0005525]  
1
  • IDAHGNC
GTPase activitydefinition[GO:0003924]  
1
  • IDAUniProtKB
Magnesium ion bindingdefinition[GO:0000287]  
1
  • NASUniProtKB
Protein bindingdefinition[GO:0005515]  
6
  • IPIUniProtKB
  • IPIIntAct
Protein heterodimerization activitydefinition[GO:0046982]  
1
  • IPIUniProtKB
GO biological process 
Apoptotic processdefinition[GO:0006915]  
1
  • NASUniProtKB
Cell growthdefinition[GO:0016049]  
1
  • NASUniProtKB
Cellular protein localizationdefinition[GO:0034613]  
  • ISSOrtholog Curator
Cellular response to amino acid stimulusdefinition[GO:0071230]  
  • ISSOrtholog Curator
GTP catabolic processdefinition[GO:0006184]  
1
  • IDAGOC
RNA splicingdefinition[GO:0008380]  
1
  • NASUniProtKB
Small GTPase mediated signal transductiondefinition[GO:0007264]  
1
  • TASUniProtKB
Transcription, DNA-templateddefinition[GO:0006351]  
1
  • NASUniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: RRAGC
GenomeRNAi: 64121
PRO: PR:Q9HB90