ARNT2 - Aryl hydrocarbon receptor nuclear translocator 2 - human protein (Function)
 
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ARNT2 »  Aryl hydrocarbon receptor nuclear translocator 2  (ARNT protein 2)
 
Protein also known as:  Class E basic helix-loop-helix protein 1 (bHLHe1).
Gene name:  ARNT2
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 31 2
GENE REF ISO

Function

 show evidences
Overview 
Specifically recognizes the xenobiotic response element (XRE).  
  • CuratedUniProtKB
GO molecular function 
Aryl hydrocarbon receptor bindingdefinition[GO:0017162]  
  • ISSOrtholog Curator
DNA bindingdefinition[GO:0003677] silver  
  • IEAOrtholog Compara
Protein heterodimerization activitydefinition[GO:0046982]  
1
  • IPIUniProtKB
  • ISSOrtholog Curator
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700]  
  • ISSOrtholog Curator
Signal transducer activitydefinition[GO:0004871] silver  
  • IEAInterPro 2 GO
GO biological process 
Central nervous system developmentdefinition[GO:0007417]  
  • ISSOrtholog Curator
In utero embryonic developmentdefinition[GO:0001701]  
  • ISSOrtholog Curator
Negative regulation of apoptotic processdefinition[GO:0043066] silver  
  • IEAOrtholog Compara
Positive regulation of cell proliferationdefinition[GO:0008284] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Positive regulation of transcription, DNA-templateddefinition[GO:0045893]  
  • ISSOrtholog Curator
Regulation of transcription, DNA-templateddefinition[GO:0006355]  
1
  • IDAMGI
Response to estradioldefinition[GO:0032355] silver  
  • IEAOrtholog Compara
Response to hypoxiadefinition[GO:0001666]  
1
  • IDAUniProtKB
Signal transductiondefinition[GO:0007165] silver  
  • IEAInterPro 2 GO
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathways:
Pathways in cancer  hsa05200+9915  
Renal cell carcinoma  hsa05211+9915  
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ARNT2
GenomeRNAi: 9915
PRO: PR:Q9HBZ2