CELSR2 - Cadherin EGF LAG seven-pass G-type receptor 2 - human protein (Function)
 
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CELSR2 »  Cadherin EGF LAG seven-pass G-type receptor 2
 
Protein also known as:  Multiple epidermal growth factor-like domains protein 3 (Multiple EGF-like domains protein 3).
Gene name:  CELSR2
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Receptor that may have an important role in cell/cell signaling during nervous system formation.  
  • CuratedUniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
  • IEAInterPro 2 GO
G-protein coupled receptor activitydefinition[GO:0004930]  
1
  • NASUniProtKB
GO biological process 
Cerebrospinal fluid secretiondefinition[GO:0033326] silver  
  • IEAOrtholog Compara
Cilium assemblydefinition[GO:0042384] silver  
  • IEAOrtholog Compara
Cilium movementdefinition[GO:0003341] silver  
  • IEAOrtholog Compara
Dendrite morphogenesisdefinition[GO:0048813]  
  • ISSOrtholog Curator
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • NASUniProtKB
Homophilic cell adhesiondefinition[GO:0007156]  
  • ISSOrtholog Curator
Neural plate anterior/posterior regionalizationdefinition[GO:0021999]  
  • ISSOrtholog Curator
Neuron migrationdefinition[GO:0001764] silver  
  • IEAOrtholog Compara
Neuropeptide signaling pathwaydefinition[GO:0007218] silver  
  • IEAInterPro 2 GO
Regulation of cell-cell adhesiondefinition[GO:0022407]  
  • ISSOrtholog Curator
Regulation of protein localizationdefinition[GO:0032880] silver  
  • IEAOrtholog Compara
Regulation of transcription, DNA-templateddefinition[GO:0006355]  
  • ISSOrtholog Curator
Ventricular system developmentdefinition[GO:0021591] silver  
  • IEAOrtholog Compara
Wnt signaling pathwaydefinition[GO:0016055]  
  • ISSOrtholog Curator
Enzymatic activity 
 
More information is available from:
 

Keywords

Molecular function 
Developmental protein  definition   [KW-0217]
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CELSR2
GenomeRNAi: 1952
PRO: PR:Q9HCU4