ACP6 - Lysophosphatidic acid phosphatase type 6 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
ACP6 »  Lysophosphatidic acid phosphatase type 6   [ EC 3.1.3.2 ]
 
Protein also known as:  Acid phosphatase 6, lysophosphatidic.
Gene name:  ACP6
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 16 2
GENE REF ISO

Function

 show evidences
Overview 
Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid.  
2
  • CuratedUniProtKB
GO molecular function 
Acid phosphatase activitydefinition[GO:0003993]  
  • IEAEC 2 GO
Lysophosphatidic acid phosphatase activitydefinition[GO:0052642]  
2
  • IDAUniProtKB
GO biological process 
Dephosphorylationdefinition[GO:0016311]  
2
  • IDAGOC
Lysobisphosphatidic acid metabolic processdefinition[GO:2001311]  
1
  • IDAUniProtKB
Phospholipid metabolic processdefinition[GO:0006644]  
1
  • IMPUniProtKB
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.1.3.2: A phosphate monoester + H(2)O an alcohol + phosphate.  
1
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Riboflavin metabolism  hsa00740+51205  
Caution 
Was originally (PubMed10506173) reported to be located in the mitochondrion, but the evidence seems to be weak and contradictory with the presence of a cleaved signal sequence.  
1
  • CuratedUniProtKB
 

Keywords

Biological process 
Lipid metabolism  definition   [KW-0443]
Phospholipid metabolism  definition   [KW-1208]
Molecular function 
Hydrolase  definition   [KW-0378]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ACP6
PRO: PR:Q9NPH0