CD93 - Complement component C1q receptor - human protein (Function)
 
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CD93 »  Complement component C1q receptor
 
Protein also known as:  Complement component 1 q subcomponent receptor 1; CD antigen CD93.
Gene name:  CD93
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.  
  • CuratedUniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
  • IEAInterPro 2 GO
Carbohydrate bindingdefinition[GO:0030246] silver  
  • IEAInterPro 2 GO
Complement component C1q bindingdefinition[GO:0001849]  
1
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
Receptor activitydefinition[GO:0004872]  
1
  • NASUniProtKB
GO biological process 
Cell-cell adhesiondefinition[GO:0016337]  
1
  • IDAUniProtKB
Macrophage activationdefinition[GO:0042116]  
1
  • NASUniProtKB
Phagocytosisdefinition[GO:0006909]  
3
  • NASUniProtKB
Viral processdefinition[GO:0016032]  
  • IEAUniProtKB KW
Enzymatic activity 
 
More information is available from:
Caution 
Has been sometimes referred to as a collectin receptor.  
  • CuratedUniProtKB
PubMed11994479 reported that C1q is not a ligand for C1QR1.  
1
  • CuratedUniProtKB
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Host-virus interaction  definition   [KW-0945]
Molecular function 
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CD93
GenomeRNAi: 22918
PRO: PR:Q9NPY3