ATP13A2 - Probable cation-transporting ATPase 13A2 - human protein (Function)
 
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ATP13A2 »  Probable cation-transporting ATPase 13A2   [ EC 3.6.3.- ]
 
Gene name:  ATP13A2
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity.  
2
  • UniProtKB
According to TCDB this is a transporter from family:
the p-type atpase (p-atpase) superfamily  3.A.3.10.7  
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • UniProtKB KW
ATPase activitydefinition[GO:0016887]  
1
  • ParkinsonsUK-UCL
Cation-transporting ATPase activitydefinition[GO:0019829] silver  
1
  • InterPro 2 GO
Metal ion bindingdefinition[GO:0046872]  
1
  • UniProtKB KW
Protein bindingdefinition[GO:0005515]  
1
  • IntAct
GO biological process 
ATP catabolic processdefinition[GO:0006200]  
2
  • GOC
  • InterPro 2 GO
Cation transmembrane transportdefinition[GO:0098655]  
1
  • InterPro 2 GO
Cellular response to manganese iondefinition[GO:0071287]  
1
  • ParkinsonsUK-UCL
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.6.3.-: ATP + H(2)O ADP + phosphate.  
1
  • UniProtKB
 

Keywords

Molecular function 
Hydrolase  definition   [KW-0378]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ATP13A2
GenomeRNAi: 23400
PRO: PR:Q9NQ11