SLC52A3 - Solute carrier family 52, riboflavin transporter, member 3 - human protein (Function)
 
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Protein
Gene
References

 
SLC52A3 »  Solute carrier family 52, riboflavin transporter, member 3
 
Protein also known as:  Riboflavin transporter 2.
Gene name:  SLC52A3
Family name: PERVR
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 28 2
GENE REF ISO

Function

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Overview 
Riboflavin transporter. Riboflavin transport is Na(+)-independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), and to a lesser extent by amiloride.  
1
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the eukaryotic riboflavin transporter (e-rft) family  9.A.53.1.2  
GO molecular function 
Riboflavin transporter activitydefinition[GO:0032217]  
1
  • IDAUniProtKB
GO biological process 
Cellular response to heatdefinition[GO:0034605] silver  
  • IEAOrtholog Compara
Riboflavin transportdefinition[GO:0032218]  
1
  • IDAUniProtKB
Sensory perception of sounddefinition[GO:0007605]  
1
  • IMPUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Vitamin digestion and absorption  hsa04977+113278  
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Metabolism  REACT_111217  
 

Biophysicochemical properties

Kinetic parameters
KM 0.98 uM for riboflavin

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: C20orf54
GenomeRNAi: 113278
PRO: PR:Q9NQ40