SLC35C2 - Solute carrier family 35 member C2 - human protein (Function)
 
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Protein
Gene
References

 
SLC35C2 »  Solute carrier family 35 member C2
 
Protein also known as:  Ovarian cancer-overexpressed gene 1 protein.
Gene name:  SLC35C2
Family name: TPT transporter » SLC35C
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 27 3
GENE REF ISO

Function

 show evidences
Overview 
May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells.  
2
  • UniProtKB
According to TCDB this is a transporter from family:
the drug/metabolite transporter (dmt) superfamily  2.A.7.9.16  
GO biological process 
Negative regulation of gene expressiondefinition[GO:0010629] silver  
1
  • Ortholog Compara
Positive regulation of Notch signaling pathwaydefinition[GO:0045747] silver  
1
  • Ortholog Compara
Protein O-linked fucosylationdefinition[GO:0036066] silver  
1
  • Ortholog Compara
Transportdefinition[GO:0006810]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SLC35C2
GenomeRNAi: 51006
PRO: PR:Q9NQQ7