GDF3 - Growth/differentiation factor 3 - human protein (Function)
 
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GDF3 »  Growth/differentiation factor 3  (GDF-3)
 
Gene name:  GDF3
Family name: TGF-beta
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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GO molecular function 
Cytokine activitydefinition[GO:0005125]  
1
  • RefGenome
Growth factor activitydefinition[GO:0008083]  
1
  • UniProtKB KW
Protein kinase bindingdefinition[GO:0019901]  
1
  • UniProtKB
Transforming growth factor beta receptor bindingdefinition[GO:0005160]  
1
  • RefGenome
GO biological process 
Cell developmentdefinition[GO:0048468]  
1
  • RefGenome
Endoderm developmentdefinition[GO:0007492] silver  
1
  • Ortholog Compara
Eye developmentdefinition[GO:0001654]  
1
  • UniProtKB
Formation of anatomical boundarydefinition[GO:0048859] silver  
1
  • Ortholog Compara
Growthdefinition[GO:0040007] silver  
1
  • InterPro 2 GO
In utero embryonic developmentdefinition[GO:0001701] silver  
1
  • Ortholog Compara
Mesoderm developmentdefinition[GO:0007498] silver  
1
  • Ortholog Compara
Negative regulation of BMP signaling pathwaydefinition[GO:0030514]  
1
  • UniProtKB
Negative regulation of epidermal cell differentiationdefinition[GO:0045605]  
1
  • UniProtKB
Notochord developmentdefinition[GO:0030903] silver  
1
  • Ortholog Compara
Positive regulation of pathway-restricted SMAD protein phosphorylationdefinition[GO:0010862]  
1
  • RefGenome
Primitive streak formationdefinition[GO:0090009] silver  
1
  • Ortholog Compara
Regulation of apoptotic processdefinition[GO:0042981]  
1
  • RefGenome
Regulation of cell fate commitmentdefinition[GO:0010453]  
1
  • UniProtKB
Regulation of MAPK cascadedefinition[GO:0043408]  
1
  • RefGenome
Response to dietary excessdefinition[GO:0002021] silver  
1
  • Ortholog Compara
Skeletal system developmentdefinition[GO:0001501]  
1
  • UniProtKB
SMAD protein signal transductiondefinition[GO:0060395]  
1
  • RefGenome
Somite rostral/caudal axis specificationdefinition[GO:0032525] silver  
1
  • Ortholog Compara
 

Keywords

Molecular function 
Cytokine  definition   [KW-0202]
Growth factor  definition   [KW-0339]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: GDF3
GenomeRNAi: 9573
PRO: PR:Q9NR23