SAR1A - GTP-binding protein SAR1a - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
SAR1A »  GTP-binding protein SAR1a
 
Protein also known as:  COPII-associated small GTPase.
Gene name:  SAR1A
Family name: Small GTPase » SAR1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 25 1
GENE REF ISO

Function

 show evidences
Overview 
Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).  
1
  • CuratedUniProtKB
GO molecular function 
GTP bindingdefinition[GO:0005525]  
  • IEAUniProtKB KW
GO biological process 
Intracellular protein transportdefinition[GO:0006886] silver  
  • IEAInterPro 2 GO
Vesicle-mediated transportdefinition[GO:0016192] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathways:
Legionellosis  hsa05134+56681  
Protein processing in endoplasmic reticulum  hsa04141+56681  
 

Keywords

Biological process 
ER-Golgi transport  definition   [KW-0931]
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 56681
PRO: PR:Q9NR31