SNRK - SNF-related serine/threonine-protein kinase - human protein (Function)
 
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SNRK »  SNF-related serine/threonine-protein kinase   [ EC 2.7.11.1 ]
 
Protein also known as:  SNF1-related kinase.
Gene name:  SNRK
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis.  
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  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
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  • IDAUniProtKB
Magnesium ion bindingdefinition[GO:0000287]  
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  • IDAUniProtKB
Protein serine/threonine kinase activitydefinition[GO:0004674]  
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  • IDAUniProtKB
GO biological process 
Myeloid cell differentiationdefinition[GO:0030099]  
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  • TASUniProtKB
Protein phosphorylationdefinition[GO:0006468]  
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  • IDAUniProtKB
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.1: ATP + a protein ADP + a phosphoprotein.  
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  • CuratedUniProtKB
It requires the following cofactor
Magnesium.  
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  • CuratedUniProtKB
It is regulated in the following manner
Activated by phosphorylation on Thr-173.  
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  • CuratedUniProtKB
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: SNRK
GenomeRNAi: 54861
PRO: PR:Q9NRH2
Chemistry
GuidetoPHARMACOLOGY: 2202