CDC42SE2 - CDC42 small effector protein 2 - human protein (Function)
 
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CDC42SE2 »  CDC42 small effector protein 2
 
Protein also known as:  Small effector of CDC42 protein 2.
Gene name:  CDC42SE2
Family name: CDC42SE/SPEC
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.  
2
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
Structural molecule activitydefinition[GO:0005198]  
1
  • IDAUniProtKB
GO biological process 
Phagocytosisdefinition[GO:0006909]  
  • IEAUniProtKB KW
Regulation of cell shapedefinition[GO:0008360]  
  • IEAUniProtKB KW
Regulation of signal transductiondefinition[GO:0009966]  
1
  • IDAUniProtKB
Note 
CDC42SE2 is mapped in the genomic region associated with schizophrenia.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Cell shape  definition   [KW-0133]
Phagocytosis  definition   [KW-0581]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 56990
PRO: PR:Q9NRR3