ADARB2 - Double-stranded RNA-specific editase B2 - human protein (Function)
 
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Protein
Gene
References

 
ADARB2 »  Double-stranded RNA-specific editase B2   [ EC 3.5.-.- ]
 
Protein also known as:  RNA-dependent adenosine deaminase 3.
Gene name:  ADARB2
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA.  
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  • UniProtKB
GO molecular function 
Adenosine deaminase activitydefinition[GO:0004000] silver  
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  • InterPro 2 GO
Double-stranded RNA bindingdefinition[GO:0003725]  
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  • PINC
Metal ion bindingdefinition[GO:0046872]  
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  • UniProtKB KW
Poly(A) RNA bindingdefinition[GO:0044822]  
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  • UniProtKB
Single-stranded RNA bindingdefinition[GO:0003727]  
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  • PINC
GO biological process 
mRNA processingdefinition[GO:0006397]  
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  • UniProtKB KW
 

Keywords

Biological process 
mRNA processing  definition   [KW-0507]
Molecular function 
Hydrolase  definition   [KW-0378]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ADARB2
GenomeRNAi: 105
PRO: PR:Q9NS39