ATP8A2 - Probable phospholipid-transporting ATPase IB - human protein (Function)
 
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ATP8A2 »  Probable phospholipid-transporting ATPase IB   [ EC 3.6.3.1 ]
 
Protein also known as:  ATPase class I type 8A member 2.
Gene name:  ATP8A2
Entry whose protein(s) existence is based on evidence at protein level
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1 26 2
GENE REF ISO

Function

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GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Cation-transporting ATPase activitydefinition[GO:0019829] silver  
  • IEAInterPro 2 GO
Magnesium ion bindingdefinition[GO:0000287] silver  
  • IEAInterPro 2 GO
Phospholipid-translocating ATPase activitydefinition[GO:0004012]  
  • IEAEC 2 GO
GO biological process 
Agingdefinition[GO:0007568] silver  
  • IEAOrtholog Compara
Axonogenesisdefinition[GO:0007409] silver  
  • IEAOrtholog Compara
Eating behaviordefinition[GO:0042755] silver  
  • IEAOrtholog Compara
Involuntary skeletal muscle contractiondefinition[GO:0003011] silver  
  • IEAOrtholog Compara
Negative regulation of cell proliferationdefinition[GO:0008285]  
1
  • TASPINC
Neuromuscular process controlling posturedefinition[GO:0050884] silver  
  • IEAOrtholog Compara
Positive regulation of multicellular organism growthdefinition[GO:0040018] silver  
  • IEAOrtholog Compara
Skin developmentdefinition[GO:0043588] silver  
  • IEAOrtholog Compara
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.6.3.1: ATP + H(2)O + phospholipid(Side 1) ADP + phosphate + phospholipid(Side 2).  
  • CuratedUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Molecular function 
Hydrolase  definition   [KW-0378]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 51761
PRO: PR:Q9NTI2