PIGV - GPI mannosyltransferase 2 - human protein (Function)
 
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Protein
Gene
References

 
PIGV »  GPI mannosyltransferase 2   [ EC 2.4.1.- ]
 
Protein also known as:  Phosphatidylinositol-glycan biosynthesis class V protein (PIG-V).
Gene name:  PIGV
Family name: PIGV
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 21 1
GENE REF ISO

Function

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Overview 
Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.  
2
  • CuratedUniProtKB
GO molecular function 
Mannosyltransferase activitydefinition[GO:0000030]  
3
  • IMPUniProtKB
GO biological process 
GPI anchor biosynthetic processdefinition[GO:0006506]  
3
  • IGIUniProtKB
Mannosylationdefinition[GO:0097502]  
3
  • IMPGOC
Enzymatic activity 
According to CAZy, this protein is belongs to the following pathway:
Glycosyltransferase Family 76  GT76  
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis  hsa00563+55650  
Metabolic pathways  hsa01100+55650  
According to Reactome, this protein belongs to the following pathway:
Synthesis of glycosylphosphatidylinositol (GPI)  REACT_952  
 

Keywords

Biological process 
GPI-anchor biosynthesis  definition   [KW-0337]
Molecular function 
Glycosyltransferase  definition   [KW-0328]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PIGV
GenomeRNAi: 55650
PRO: PR:Q9NUD9