ABHD10 - Mycophenolic acid acyl-glucuronide esterase, mitochondrial - human protein (Function)
 
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Protein
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ABHD10 »  Mycophenolic acid acyl-glucuronide esterase, mitochondrial
 
Gene name:  ABHD10
Family name: AB hydrolase
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate.  
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  • CuratedUniProtKB
GO molecular function 
Hydrolase activity, hydrolyzing O-glycosyl compoundsdefinition[GO:0004553]  
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  • IDABHF-UCL
GO biological process 
Glucuronoside catabolic processdefinition[GO:0019391]  
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  • IDABHF-UCL
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 3.1.1.93: Mycophenolic acid O-acyl-glucuronide + H(2)O mycophenolate + D-glucuronate.  
1
  • CuratedUniProtKB
 
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Keywords

Molecular function 
Hydrolase  definition   [KW-0378]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 55347
PRO: PR:Q9NUJ1