ANO10 - Anoctamin-10 - human protein (Function)
 
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Protein
Gene
References

 
ANO10 »  Anoctamin-10
 
Protein also known as:  Transmembrane protein 16K.
Gene name:  ANO10
Family name: Anoctamin
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.  
3
  • UniProtKB
GO molecular function 
Calcium activated cation channel activitydefinition[GO:0005227]  
1
  • UniProtKB
Contradiction  Intracellular calcium activated chloride channel activitydefinition[GO:0005229]  
2
  • UniProtKB
GO biological process 
Cation transmembrane transportdefinition[GO:0098655]  
1
  • GOC
Cation transportdefinition[GO:0006812]  
1
  • UniProtKB
Chloride transmembrane transportdefinition[GO:1902476]  
1
  • GOC
Chloride transportdefinition[GO:0006821]  
1
  • UniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathways:
Orphan transporters  REACT_268444  
Stimuli-sensing channels  REACT_160189  
Note 
The term 'anoctamin' was coined because these channels are anion selective and have eight (OCT) transmembrane segments. There is some dissatisfaction in the field with the Ano nomenclature because it is not certain that all the members of this family are anion channels or have the 8-transmembrane topology.  
1
  • UniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 55129
PRO: PR:Q9NW15