ANO10 - Anoctamin-10 - human protein (Function)
 
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Protein
Gene
References

 
ANO10 »  Anoctamin-10
 
Protein also known as:  Transmembrane protein 16K.
Gene name:  ANO10
Family name: Anoctamin
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 27 5
GENE REF ISO

Function

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Overview 
Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.  
2
  • CuratedUniProtKB
GO molecular function 
Calcium activated cation channel activitydefinition[GO:0005227]  
1
  • IDAUniProtKB
Contradiction  Intracellular calcium activated chloride channel activitydefinition[GO:0005229]  
2
  • IDAUniProtKB
GO biological process 
Cation transportdefinition[GO:0006812]  
1
  • IDAUniProtKB
Cell deathdefinition[GO:0008219]  
  • IEAUniProtKB KW
Chloride transmembrane transportdefinition[GO:1902476]  
1
  • IDAGOC
Chloride transportdefinition[GO:0006821]  
1
  • IDAUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
Stimuli-sensing channels  REACT_160189  
Note 
The term 'anoctamin' was coined because these channels are anion selective and have eight (OCT) transmembrane segments. There is some dissatisfaction in the field with the Ano nomenclature because it is not certain that all the members of this family are anion channels or have the 8-transmembrane topology.  
  • CuratedUniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 55129
PRO: PR:Q9NW15