FKBP14 - Peptidyl-prolyl cis-trans isomerase FKBP14 - human protein (Function)
 
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FKBP14 »  Peptidyl-prolyl cis-trans isomerase FKBP14   [ EC 5.2.1.8 ]  (PPIase FKBP14)
 
Protein also known as:  22 kDa FK506-binding protein (FKBP-22).
Gene name:  FKBP14
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
PPIases accelerate the folding of proteins during protein synthesis.  
  • CuratedUniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
  • IEAInterPro 2 GO
FK506 bindingdefinition[GO:0005528] silver  
  • IBARefGenome
Peptidyl-prolyl cis-trans isomerase activitydefinition[GO:0003755] silver  
  • IBARefGenome
GO biological process 
Peptidyl-proline modificationdefinition[GO:0018208] silver  
  • IBARefGenome
Protein foldingdefinition[GO:0006457]  
  • IEAUniProtKB KW
Protein peptidyl-prolyl isomerizationdefinition[GO:0000413] silver  
  • IBARefGenome
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 5.2.1.8: Peptidylproline (omega180) peptidylproline (omega0).  
  • CuratedUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
Metabolism of proteins  REACT_17015  
 

Keywords

Molecular function 
Isomerase  definition   [KW-0413]
Rotamase  definition   [KW-0697]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 55033
PRO: PR:Q9NWM8