ASIC5 - Acid-sensing ion channel 5 - human protein (Function)
 
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ASIC5 »  Acid-sensing ion channel 5  (ASIC5)
 
Protein also known as:  Amiloride-sensitive cation channel 5.
Gene name:  ASIC5
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.  
1
  • CuratedUniProtKB
GO molecular function 
Hydrogen ion channel activitydefinition[GO:0015252] silver  
  • IEAOrtholog Compara
Ligand-gated sodium channel activitydefinition[GO:0015280] silver  
  • IEAOrtholog Compara
GO biological process 
Proton transportdefinition[GO:0015992] silver  
  • IEAOrtholog Compara
Sodium ion transmembrane transportdefinition[GO:0035725] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathway:
Stimuli-sensing channels  REACT_160189  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Sodium transport  definition   [KW-0739]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Sodium channel  definition   [KW-0894]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 51802
PRO: PR:Q9NY37