B3GNT2 - UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 - human protein (Function)
 
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Protein
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References

 
B3GNT2 »  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2   [ EC 2.4.1.- ]  (BGnT-2)
 
Protein also known as:  UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7.
Gene name:  B3GNT2
Family name: Glycosyltransferase 31
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 32 2
GENE REF ISO

Function

 show evidences
Overview 
Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains.  
1
  • CuratedUniProtKB
GO molecular function 
Galactosyltransferase activitydefinition[GO:0008378] silver  
  • IEAInterPro 2 GO
GO biological process 
Axon guidancedefinition[GO:0007411] silver  
  • IEAOrtholog Compara
Sensory perception of smelldefinition[GO:0007608] silver  
  • IEAOrtholog Compara
Enzymatic activity 
It requires the following cofactor
Manganese.  
1
  • CuratedUniProtKB
According to CAZy, this protein is belongs to the following pathway:
Glycosyltransferase Family 31  GT31  
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Glycosaminoglycan biosynthesis - keratan sulfate  hsa00533+10678  
Glycosphingolipid biosynthesis - lacto and neolacto series  hsa00601+10678  
Metabolic pathways  hsa01100+10678  
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Metabolism  REACT_111217  
Metabolism of proteins  REACT_17015  
Caution 
Was indicated as B3Gal-T6 in submitted DNA entries.  
  • CuratedUniProtKB
 

Keywords

Molecular function 
Glycosyltransferase  definition   [KW-0328]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: B3GNT2
GenomeRNAi: 10678
PRO: PR:Q9NY97