TAS2R16 - Taste receptor type 2 member 16 - human protein (Function)
 
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Protein
Gene
References

 
TAS2R16 »  Taste receptor type 2 member 16  (T2R16)
 
Gene name:  TAS2R16
Entry whose protein(s) existence is based on evidence at protein level
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1 29 1
GENE REF ISO

Function

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Overview 
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.  
2
  • CuratedUniProtKB
GO molecular function 
Bitter taste receptor activitydefinition[GO:0033038]  
2
  • IDAUniProtKB
  • IDAHGNC
Protein bindingdefinition[GO:0005515]  
1
  • IPIHGNC
GO biological process 
Detection of chemical stimulus involved in sensory perception of bitter tastedefinition[GO:0001580]  
2
  • IDAUniProtKB
  • IDAHGNC
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • ICHGNC
Pathways 
According to KEGG, this protein belongs to the following pathway:
Taste transduction  hsa04742+50833  
According to Reactome, this protein belongs to the following pathways:
Class C/3 (Metabotropic glutamate/pheromone receptors)  REACT_18319  
G alpha (i) signalling events  REACT_19231  
Note 
Several bitter taste receptors are expressed in a single taste receptor cell.  
  • CuratedUniProtKB
Confers bitter perception of salicin to non-taster mice.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Sensory transduction  definition   [KW-0716]
Taste  definition   [KW-0919]
Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: TAS2R16
GenomeRNAi: 50833
PRO: PR:Q9NYV7