TAS2R7 - Taste receptor type 2 member 7 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
TAS2R7 »  Taste receptor type 2 member 7  (T2R7)
 
Protein also known as:  Taste receptor family B member 4 (TRB4).
Gene name:  TAS2R7
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 16 1
GENE REF ISO

Function

 show evidences
Overview 
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.  
  • CuratedUniProtKB
GO molecular function 
Bitter taste receptor activitydefinition[GO:0033038]  
1
  • IDAUniProtKB
Taste receptor activitydefinition[GO:0008527]  
1
  • TASUniProtKB
GO biological process 
Detection of chemical stimulus involved in sensory perception of bitter tastedefinition[GO:0001580]  
1
  • IDAUniProtKB
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathway:
Taste transduction  hsa04742+50837  
According to Reactome, this protein belongs to the following pathways:
Class C/3 (Metabotropic glutamate/pheromone receptors)  REACT_18319  
G alpha (i) signalling events  REACT_19231  
Note 
Several bitter taste receptors are expressed in a single taste receptor cell.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Sensory transduction  definition   [KW-0716]
Taste  definition   [KW-0919]
Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: TAS2R7
GenomeRNAi: 50837
PRO: PR:Q9NYW3