PODXL2 - Podocalyxin-like protein 2 - human protein (Function)
 
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Protein
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References

 
PODXL2 »  Podocalyxin-like protein 2
 
Protein also known as:  Endoglycan.
Gene name:  PODXL2
Family name: Podocalyxin
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins.  
1
  • CuratedUniProtKB
GO molecular function 
Glycosaminoglycan bindingdefinition[GO:0005539]  
1
  • TASPINC
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
GO biological process 
Leukocyte tethering or rollingdefinition[GO:0050901]  
1
  • IDAUniProtKB
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 50512
PRO: PR:Q9NZ53